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Overview

Uniprot IDA0A8W4F9W9
Protein NameDNA-directed RNA polymerases I, II, and III subunit RPABC5
Gene NamePOLR2L
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
12 VRCFTCGKIVGNKWE

Function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively

Protein Sequence

10 MIIPVRCFTC 20 GKIVGNKWEA 30 YLGLLQAEYT 40 EGDALDALGL 50 KRYCCRRMLL 60 AHVDLIEKLL NYAPLEK

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005736 RNA polymerase I complex
Cellular Component GO:0005665 RNA polymerase II, core complex
Cellular Component GO:0005666 RNA polymerase III complex
Molecular Function GO:0003677 DNA binding
Molecular Function GO:0003899 DNA-directed RNA polymerase activity
Molecular Function GO:0008270 zinc ion binding
Biological Process GO:0006360 transcription by RNA polymerase I
Biological Process GO:0006366 transcription by RNA polymerase II
Biological Process GO:0042797 tRNA transcription by RNA polymerase III

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.