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Overview

Uniprot IDA0A8W4FA69
Protein NameAP-1 complex subunit mu-1
Gene NameAP1M1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
400 GIQVRYLKIIEKSGY
64 LYLVATSKKNACVSL

Function

Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules

Protein Sequence

10 MFPSAVVLIC 20 RNYRGDVDMS 30 EVEHFMPILM 40 EKEEEGMLSP 50 ILAHGGVRFM 60 WIKHNNLYLV 70 ATSKKNACVS 80 LVFSFLYKVV 90 QVFSEYFKEL 100 EEESIRDNFV 110 IIYELLDELM 120 DFGYPQTTDS 130 KILQEYITQE 140 GHKLETGAPR 150 PPATVTNAVS 160 WRSEGIKYRK 170 NEVFLDVIES 180 VNLLGKYPGV 190 GLLGHMVSAN 200 GNVLRSEIVG 210 SIKMRVFLSG 220 MPELRLGLND 230 KVLFDNTGRG 240 KSKSVELEDV 250 KFHQCVRLSR 260 FENDRTISFI 270 PPDGEFELMS 280 YRLNTHVKPL 290 IWIESVIEKH 300 SHSRIEYMIK 310 AKSQFKRRST 320 ANNVEIHIPV 330 PNDADSPKFK 340 TTVGSVKWVP 350 ENSEIVWSIK 360 SFPGGKEYLM 370 RAHFGLPSVE 380 AEDKEGKPPI 390 SVKFEIPYFT 400 TSGIQVRYLK 410 IIEKSGYQAL 420 PWVRYITQNG DYQLRTQ

Gene Ontology

Classification GO ID Description
Cellular Component GO:0030131 clathrin adaptor complex
Cellular Component GO:0030665 clathrin-coated vesicle membrane
Cellular Component GO:0005802 trans-Golgi network
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:0016192 vesicle-mediated transport

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.