Search Results

Overview

Uniprot IDA0A8W4FAR4
Protein NameTubulin alpha chain
Gene NameTUBA1B
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
113 PEQLITGKEDAANNY
180 RLSVDYGKKSKLEFS
343 YRGDVVPKDVNAAIA
353 NAAIATIKTKRSIQF
387 VPGGDLAKVQRAVCM
411 AWARLDHKFDLMYAK
418 KFDLMYAKRAFVHWY
77 FSETGAGKHVPRAVF

Function

Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin

Protein Sequence

10 ARERWESPPL 20 QSAHACWGRE 30 CISIHVGQAG 40 VQIGNACWEL 50 YCLEHGIQPD 60 GQMPSDKTIG 70 GGDDSFNTFF 80 SETGAGKHVP 90 RAVFVDLEPT 100 VIDEVRTGTY 110 RQLFHPEQLI 120 TGKEDAANNY 130 ARGHYTIGKE 140 IIDLVLDRIR 150 KLADQCTGLQ 160 GFLVFHSFGG 170 GTGSGFTSLL 180 MERLSVDYGK 190 KSKLEFSIYP 200 APQVSTAVVE 210 PYNSILTTHT 220 TLEHSDCAFM 230 VDNEAIYDIC 240 RRNLDIERPT 250 YTNLNRLISQ 260 IVSSITASLR 270 FDGALNVDLT 280 EFQTNLVPYP 290 RIHFPLATYA 300 PVISAEKAYH 310 EQLSVAEITN 320 ACFEPANQMV 330 KCDPRHGKYM 340 ACCLLYRGDV 350 VPKDVNAAIA 360 TIKTKRSIQF 370 VDWCPTGFKV 380 GINYQPPTVV 390 PGGDLAKVQR 400 AVCMLSNTTA 410 IAEAWARLDH 420 KFDLMYAKRA 430 FVHWYVGEGM 440 EEGEFSEARE 450 DMAALEKDYE 460 EVGVDSVEGE GEEEGEEY

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005874 microtubule
Molecular Function GO:0005525 GTP binding
Molecular Function GO:0016787 hydrolase activity
Molecular Function GO:0005200 structural constituent of cytoskeleton
Biological Process GO:0007017 microtubule-based process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.