Search Results
Overview
| Uniprot ID | A0A8W4FBG7 |
|---|---|
| Protein Name | Pyruvate dehydrogenase E1 component subunit beta |
| Gene Name | PDHB |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 156 | PWSSEDAKGLIKSAI |
| 199 | DFLIPIGKAKIERQG |
| 326 | KDIIFAIKKTLNI** |
Function
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2
Protein Sequence
10
RAAVTVRDAI
20
NQGMDEELER
30
DEKVFLLGEE
40
VAQYDGAYKV
50
SRGLWKKYGD
60
KRIIDTPISE
70
VSLSSGSRPL
80
RRHAGLRPIC
90
EFMTFNFSMQ
100
AIDQVINSAA
110
KTYYMSGGLQ
120
SVPIVFRGPN
130
GASAGVAAQH
140
SQCFAAWYGH
150
CPGLKVVSPW
160
SSEDAKGLIK
170
SAIRDNNPVV
180
VLENELMYGV
190
PFELPAEAQS
200
KDFLIPIGKA
210
KIERQGTHIT
220
IVSHSRPVGH
230
CLEAATVLSK
240
EGIECEVINM
250
RTIRPMDIET
260
IEASVMKTTH
270
LITVEGGWPQ
280
FGIGAEICAR
290
IMEGPAFNFL
300
DAPAVRVTGA
310
DVPMPYAKIL
320
EDNSVPQVKD
330
IIFAIKKTLN
I
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0045254 | pyruvate dehydrogenase complex |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0004739 | pyruvate dehydrogenase (acetyl-transferring) activity |
| Biological Process | GO:0006006 | glucose metabolic process |
| Biological Process | GO:0006086 | pyruvate decarboxylation to acetyl-CoA |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.