Search Results
Overview
| Uniprot ID | A0A8W4FBN2 |
|---|---|
| Protein Name | Mevalonate kinase |
| Gene Name | MVK |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 188 | TKVPRSTKALVASVR |
Function
Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis
Protein Sequence
10
MLSQVLLVSA
20
PGKVILHGEH
30
SVVHGKVALA
40
VALNLRTFLR
50
LQPHNSGKVS
60
LRLPNIGIQQ
70
TWDVARLQLL
80
DTSFLEQGDL
90
TEQVEKLKEV
100
AGFSKDSTNH
110
DCLAVPAFLY
120
LYLTICRSQR
130
WTEENLELIN
140
KWAFQGERVI
150
HGNPSGVDNA
160
VSTWGGALRY
170
QQGKISPLKR
180
LPTLEILLVN
190
TKVPRSTKAL
200
VASVRNRMLK
210
FPEIIAPLLA
220
SMDAISLECE
230
RVLGEMAAAP
240
ALEHYLVLEE
250
LIDMNQHHLN
260
ALGVGHASLD
270
QLCQVTTAHG
280
LHSKLTGAGG
290
GGCGITLLRP
300
DLERPEVEDT
310
KQALTSCGFD
320
CWETSIGAPG
330
VFVHMAASLD
340
ASVQQALGDL
R
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0004496 | mevalonate kinase activity |
| Biological Process | GO:0006695 | cholesterol biosynthetic process |
| Biological Process | GO:0008299 | isoprenoid biosynthetic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.