Search Results
Overview
| Uniprot ID | A0A8W4FDE6 |
|---|---|
| Protein Name | Peroxiredoxin-5 |
| Gene Name | PRDX5 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 19 | FEGEPEKKVNLAELF |
| 60 | VEQAEALKAKGIQVV |
Function
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events
Protein Sequence
10
LVGDAIPSVV
20
VFEGEPEKKV
30
NLAELFKGKK
40
GVLFGVPGAF
50
TPGCSKTHLP
60
GFVEQAEALK
70
AKGIQVVACL
80
SVNDVFVTEM
90
WGRAHNTEGK
100
VRLLADPTGA
110
FGKETDLLLD
120
DSLVSLFGNR
130
RLKRFSMVIE
140
DGIVKSLNVE
150
PDGTGLTCSL
APNIISQL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005782 | peroxisomal matrix |
| Molecular Function | GO:0008379 | thioredoxin peroxidase activity |
| Biological Process | GO:0034599 | cellular response to oxidative stress |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.