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Overview

Uniprot ID	A0A8W4FDV0
Protein Name	Ribosome biogenesis protein BOP1
Gene Name	BOP1
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
486	RLRVCHGKPVTQVTW

Function

Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome

Protein Sequence

10 MRDPSHVCDL 20 RCSSRQRQIL 30 NPLSKARDRT 40 HNLTVPLPRG 50 EEQHSRMEKA 60 TGQQAGTPSP 70 RTQVASVPGE 80 DEYAEDSSDE 90 EDIRNTVGNV 100 PLAWYEDFPH 110 VGYDLDGRRI 120 YKPLRTQDEL 130 DQFLDKMDNP 140 DYWRTVQDRT 150 TGHDVRLTDE 160 QVALVQRLQR 170 GQFGDVSFDP 180 YEPSVDFFSG 190 DLMIHPVTNR 200 PADKRSFIPS 210 LVEKEKVSRM 220 VHAIKMGWIQ 230 PRRPRDPTPS 240 FYDLWAQEDP 250 NAVLGRHKMH 260 VPAPKLALPG 270 HAESYNPPPE 280 YLPSEEERLA 290 WDQQEPEERK 300 LSFLPRQFSS 310 LRAVPAYGRF 320 IQERFERCLD 330 LYLCPRQRKM 340 RVNVDPEDLI 350 PKLPRPRDLQ 360 PFPTCQALVY 370 RGHSDLVRCL 380 SVSPGGQWLA 390 SGSDDGSVRL 400 WEAATARCVR 410 TVPVGGVVRS 420 VAWNPQPAIC 430 LVAVAVEDTV 440 LLLNPTVGDR 450 LAVSSTDQLL 460 SAYTPPAEPA 470 AQPAQWLEAS 480 EEERRGGLRL 490 RVCHGKPVTQ 500 VTWHGRGDYL 510 AVVLATTGHT 520 QVLIHQLSRR 530 RSQSPFRRSH 540 GQVQRVAFHP 550 VRPFLLVASQ 560 RSVRLYHLLR 570 QELTKKLLPN 580 CKWVSSLAVH 590 PAGDNVICGS 600 YDSKLVWFDL 610 DLSTKPYRVL 620 RHHKKALRAV 630 AFHPRYPLFA 640 SGSDDGSVIV 650 CHGMVYNDLL 660 QNPLLVPVKV 670 LKGHALTRDL 680 GVLDVAFHPT 690 QPWVFSAGAD GTVRLFS

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005730	nucleolus
Cellular Component	GO:0005654	nucleoplasm
Cellular Component	GO:0030687	preribosome, large subunit precursor
Molecular Function	GO:0043021	ribonucleoprotein complex binding
Biological Process	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Biological Process	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.