Search Results
Overview
| Uniprot ID | A0A8W4FEN3 |
|---|---|
| Protein Name | Leucine-rich repeat-containing protein 59 |
| Gene Name | LRRC59 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 111 | FAQLKSLKWLDLKDN |
| 135 | AGDCLDEKQCKQCAN |
| 143 | QCKQCANKVLQHMKA |
| 149 | NKVLQHMKAVQADQE |
| 207 | RKEYDALKAAKREQE |
| 7 | *MTKAGSKGGNLRDK |
| 71 | LVKLDLSKNKLRQLP |
Function
Required for nuclear import of FGF1, but not that of FGF2. Might regulate nuclear import of exogenous FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and possibly through, the nuclear pores
Protein Sequence
10
MTKAGSKGGN
20
LRDKLDGNEL
30
DLSLSDLNEV
40
PVKELAALSK
50
ATILDLSCNK
60
LTTLPSEFCG
70
LTHLVKLDLS
80
KNKLRQLPAD
90
FGRLVNLQHL
100
DLLNNRLVTL
110
PVSFAQLKSL
120
KWLDLKDNPL
130
DPVLAKVAGD
140
CLDEKQCKQC
150
ANKVLQHMKA
160
VQADQERERQ
170
RRLEIDREAE
180
KKWEAKQRAK
190
EAQERELRKR
200
EKAEEKERRR
210
KEYDALKAAK
220
REQEKKPKKE
230
TNQAPKSKSG
240
SRPRKPPPRK
250
HTRSWAVLKL
260
LLLLLLCVAG
270
GLVACRVTEL
280
QQQPLCTSVN
290
TIYDNAVRGL
300
RSHDIVQSCS
310
GTEWAPAFQH
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Cellular Component | GO:0042645 | mitochondrial nucleoid |
| Cellular Component | GO:0005635 | nuclear envelope |
| Biological Process | GO:0035556 | intracellular signal transduction |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.