Search Results
Overview
| Uniprot ID | A0A8W4FEV5 |
|---|---|
| Protein Name | Gephyrin |
| Gene Name | GPHN |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 285 | TASCPTPKVQSRCSS |
| 99 | PVCGIRGKTLIINLP |
Function
Also has a catalytic activity and catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released
Protein Sequence
10
MATEGMILTN
20
HDHQIRVGVL
30
TVSDSCFRNL
40
AEDRSGINLK
50
DLYYKVWFID
60
SIIYKYFKLI
70
LLLLIEREAP
80
GMALAMLMGS
90
LNVTPLGMLS
100
RPVCGIRGKT
110
LIINLPGSKK
120
GSQECFQFIL
130
PALPHAIDLL
140
RDAIVKVKEV
150
HDELEDLPSP
160
PPPLSPPPTT
170
SPHKQTEDKG
180
VQCEEEEEEK
190
KDSGVASTED
200
SSSSHITAAA
210
IAAKKHPFYT
220
SPAVIMAHGE
230
QPIPGLISYS
240
HDATGSAEEP
250
IPDSIISRGV
260
QVLPRDTASL
270
STTPSESPRA
280
QATSRLSTAS
290
CPTPKVQSRC
300
SSKENILRAS
310
HSAVDITKVA
320
RRHRMSPFPL
330
TSMDKAFITV
340
LEMTPVLGTE
350
IINYRDGMGR
360
VLAQDVYAKD
370
NLPPFPASVK
380
DGYAVRAADG
390
PGDRFIIGES
400
QAGEQPTQTV
410
MPGQVMRVTT
420
GAPIPCGADA
430
VVQVEDTELI
440
RESDDGTEEL
450
EVRILVQARP
460
GQDIRPIGHD
470
IKRGECVLAK
480
GTHMGPSEIG
490
LLATVGVTEV
500
EVNKFPVVAV
510
MSTGNELLNP
520
EDDLLPGKIR
530
DSNRSTLLAT
540
IQEHGYPTIN
550
LGIVGDNPDD
560
LLNALNEGIS
570
RADVIITSGG
580
VSMGEKDYLK
590
QVLDIDLHAQ
600
IHFGRVFMKP
610
GLPTTFATLD
620
IDGVRKIIFA
630
LPGNPVSAVV
640
TCNLFVVPAL
650
RKMQGILDPR
660
PTIIKARLSC
670
DVKLDPRPEY
680
HRCILTWHHQ
690
EPLPWAQSTG
700
NQMSSRLMSM
710
RSANGLLMLP
720
PKTEQYVELH
730
KGEVVDVMVI
GRL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005856 | cytoskeleton |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0030425 | dendrite |
| Cellular Component | GO:0014069 | postsynaptic density |
| Cellular Component | GO:0045211 | postsynaptic membrane |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0061598 | molybdopterin adenylyltransferase activity |
| Molecular Function | GO:0061599 | molybdopterin molybdotransferase activity |
| Biological Process | GO:0006777 | Mo-molybdopterin cofactor biosynthetic process |
| Biological Process | GO:0072657 | protein localization to membrane |
| Biological Process | GO:0050808 | synapse organization |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.