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Overview

Uniprot IDA0A8W4FG18
Protein NameD-dopachrome decarboxylase
Gene NameDDT
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
33 ATASILGKPEDRVNV

Function

Tautomerization of D-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI)

Protein Sequence

10 MPFVELDTNL 20 PADRLAAGLE 30 KRLCAATASI 40 LGKPEDRVNV 50 TVRPGLVMAL 60 NGSAEPAAQL 70 LVSSIGVVGT 80 AEENRVHSAR 90 FFEFLTKELD 100 LAQDRIIIRF 110 LPLEPWQIGK KGTIMTFL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005615 extracellular space
Molecular Function GO:0033981 D-dopachrome decarboxylase activity
Molecular Function GO:0050178 phenylpyruvate tautomerase activity
Molecular Function GO:0002020 protease binding
Biological Process GO:0042438 melanin biosynthetic process
Biological Process GO:0050729 positive regulation of inflammatory response

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.