Search Results
Overview
| Uniprot ID | A0A8W4FG81 |
|---|---|
| Protein Name | 26S proteasome non-ATPase regulatory subunit 5 |
| Gene Name | PSMD5 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 304 | EGKQVLQKTGTRFER |
| 328 | KNASTELKIRCLDAV |
| 55 | VHVARNLKVDLQRGL |
| 70 | THTNDSVKILTLSQV |
Function
Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5
Protein Sequence
10
MAAQVLALLR
20
EVSRLEAPLE
30
ELRHAAELEQ
40
TTLCVSILER
50
LLQALEPVHV
60
ARNLKVDLQR
70
GLTHTNDSVK
80
ILTLSQVGRI
90
VDNSDAVTEI
100
LNNAELLKQI
110
VYCIGGENLS
120
VAKAAIKSLS
130
RISLTQAGLE
140
ALFESNLLDD
150
LKSVMKTNDI
160
VRYRVYELIV
170
EISSVSPESL
180
NYCTTSGLVT
190
QLLRELTGED
200
VLVRATCIEM
210
VTSLAYTHHG
220
RQYLAQEGVI
230
DQISNIIVGA
240
DSDPFSSFYL
250
PGFVKFFGNL
260
AIMDSPQQIC
270
ERYPVFVEKV
280
FEMTESQDPT
290
MIGVAVDTIG
300
ILGSNVEGKQ
310
VLQKTGTRFE
320
RLLMKIGYQA
330
KNASTELKIR
340
CLDAVSSLFY
350
LPPEQQTDDL
360
LRMTESWFSS
370
LSRDPLELFR
380
GISNQPFPEL
390
HCAALKVFTA
400
IANQPWAQKL
410
MFNSPGFVEY
420
VMDRSVEHDK
430
ASKDAKYELV
440
KALANSKTIA
450
EIFGNPNYLR
460
LRTYLSEGPY
470
YVKPISTTAV
EGAE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Biological Process | GO:0043248 | proteasome assembly |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.