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Overview

Uniprot IDA0A8W4FH08
Protein NameTransducin beta-like protein 3
Gene NameTBL3
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
690 RDPESCEKLEATVLQ

Function

Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome

Protein Sequence

10 TGQGFAGVGG 20 NDMSSRGCKV 30 SPGLRPFCHQ 40 LDQTGQHLFC 50 VCGTRVNILD 60 VASGAVLRSL 70 EQEDQEDITA 80 FDLSPDDEVL 90 VTATRALLLA 100 QWAWREGSIV 110 RLWKAIHTAP 120 VAAMAFDPTS 130 TLLATGGCDG 140 AVRVWDVVRH 150 YGTHHFRGSP 160 GVVHLVAFHP 170 DPARLLLFSS 180 AADASIRVWS 190 LQDRSCLAVL 200 TAHYSAVTSV 210 TFSADGYTMI 220 SSGRDKICTV 230 WDLQSLQATK 240 TVPVFESVEA 250 AVLLPEEPAP 260 ELGVKSTGLH 270 FLTAGDQGIL 280 RVWEAASGQC 290 VHAQPRLPGP 300 GQELTHCALA 310 RAAGLLLSVT 320 ADHNLLLYEA 330 RSLQLQKQFA 340 GYSEEVLDVR 350 FLGPENSHVV 360 VASNSPCLKV 370 FELQTSACQI 380 LHGHTDIVLA 390 LDVFRKGWLF 400 ASCAKDQSIR 410 IWRINKAGLV 420 ACVAQGSGHT 430 HSVGTICCSR 440 LKESFLVTGS 450 QDCTVKLWPL 460 PEALPSRSTA 470 PDSGPVLLQA 480 QATQRCHDKD 490 INSVAIAPND 500 KLLATGSQDR 510 TAKLWALPQC 520 QLLGIFSGHR 530 RGLWCVQFSP 540 MDQVLATASA 550 DGTVKLWALQ 560 DFSCLKTFEG 570 HDASVGASRC 580 RPSGSDGLVK 590 LWTIKSNECV 600 RTLDAHEDKV 610 WGLHCSRLDD 620 RALTAASDSR 630 VILWKDVTEE 640 EQAEEEARRE 650 EEVVRQQELD 660 NLLHEKRYLR 670 ALGLAISLDR 680 PHTVLTVIQA 690 IRRDPESCEK 700 LEATVLQLRR 710 DQKEALLRFC 720 VTWNTNSRHC 730 HEAQAVLGML 740 LRHEAPEELL 750 AYDGVRASLE 760 ALLPYTERHF 770 QRLSRTLQAA 780 AFLDFLWHSM 790 KLPTLPAAPP AL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0032040 small-subunit processome
Biological Process GO:0006364 rRNA processing

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.