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Overview

Uniprot IDA0A8W4FHZ2
Protein NameProtein transport protein Sec31A
Gene NameSEC31A
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
1071 PTEKITKKPIPDEHL
1101 SATDPQTKRKLDDAS
1103 TDPQTKRKLDDASKR
111 SKIIAGDKEVVIAQN
206 RKNEPIIKVSDHSNR
441 VTEQEFLKRSDQLQQ
461 GFVSYCQKKIDASQT
462 FVSYCQKKIDASQTE
489 FEDDSRGKYLELLGY
582 TQKKYFAKSQSKITR
609 IVESCDLKNWREALA
71 SSSHRYHKLIWGPHK
764 PGHQESPKSPYERQQ

Function

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules

Protein Sequence

10 MKLKEVDRTA 20 MQAWSPAQNH 30 PIYLATGTSA 40 QQLDATFSTS 50 ASLEIFELDL 60 SDPSLDMKSC 70 ATFSSSHRYH 80 KLIWGPHKMD 90 SQGNVSGVLI 100 AGGENGNTIL 110 YDPSKIIAGD 120 KEVVIAQNDK 130 HTGPVRALDV 140 NIFQTNLVAS 150 GANESEIYIW 160 DLNNFATPMT 170 PGAKTQPPED 180 ISCIAWNRQV 190 QHILASASPS 200 GRATVWDLRK 210 NEPIIKVSDH 220 SNRMHCSGLA 230 WHPDVATQMV 240 LASEDDRLPV 250 VQMWDLRFAS 260 SPLRVLENHA 270 RGILAIAWSM 280 ADPELLLTCG 290 KDAKILCSNP 300 NTGEVLYELP 310 TNTQWCFDIQ 320 WCPRNPAVLS 330 AASFDGRISV 340 YSIMGGSADG 350 LRQKQVDKLS 360 SSFGNLDPFG 370 TGQPLPPLQI 380 PQQTAQHSVV 390 LPLKKPPKWI 400 RRPVGASFSF 410 GGKLVTFASV 420 RAQPPQGAEP 430 QQPQQHHVLI 440 SQVVTEQEFL 450 KRSDQLQQVV 460 QSQGFVSYCQ 470 KKIDASQTEF 480 EKNVWSFLKV 490 NFEDDSRGKY 500 LELLGYRKED 510 LGKKRIKEEK 520 QESEFLPSAG 530 GTFNISVSGD 540 IDGLITQALL 550 TGDFESAVDL 560 CLHDNRMADA 570 IILAIAGGQE 580 LLARTQKKYF 590 AKSQSKITRL 600 ITAVVMKDWK 610 EIVESCDLKN 620 WREALAAVLT 630 YAKPDEFSAL 640 CDLLGTRLES 650 EGDSLLQTQA 660 CLCYICAGNV 670 EKLVACWTKA 680 QDGSNPLSLQ 690 DLIEKVVILR 700 RAVQLTQAVD 710 TNAVGVLLAE 720 KMSQYASLLA 730 AQGSIAAALA 740 FLPENTNQPN 750 IVQLRDRLCR 760 AQGDPAPGHQ 770 ESPKSPYERQ 780 QLPKGRPGPV 790 AGHTQMPRVP 800 AQQYYPHGEN 810 PPPPAFVMHG 820 SGHPNAGAPT 830 PLGHVHTQVP 840 PYPQPQPYQP 850 AQQYSLGTGG 860 SAVYRPQQPV 870 APSASNTYPN 880 TPYISSASSY 890 PGQSQLYTAQ 900 HQASPPTSSP 910 TASFPLPPSS 920 GASFQHGGPG 930 APPSSSAYAL 940 PPGTTGTLPA 950 ASELPASQRT 960 GPQNGWNDPP 970 ALNRVPKKKK 980 MPENFTPPVP 990 ITSPIMNPLG 1000 DPQSQMLQQQ 1010 PSAPVPLSSQ 1020 ASFLQPHLPG 1030 GQPFHGILQP 1040 LGQVGMPPSF 1050 SKPNVEGAPG 1060 APIGNTIQHV 1070 QSLPTEKITK 1080 KPIPDEHLVL 1090 KTTFEDLIQR 1100 CLSSATDPQT 1110 KRKLDDASKR 1120 LEFLYDKLRE 1130 QTLSPTIISG 1140 LHNIARSIET 1150 RNYSKGLTIH 1160 THVVSTSNFS 1170 ETSAFMPVLK 1180 VVLTQAIKLG V

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005789 endoplasmic reticulum membrane
Cellular Component GO:0012507 ER to Golgi transport vesicle membrane
Biological Process GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
Biological Process GO:0015031 protein transport

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.