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Overview

Uniprot IDA0A8W4FII6
Protein Name-
Gene NameRFC2
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
111 RLLNVIEKEKVPYTD
35 QQKVTLPKGRHKIII
95 CAVLRYTKLTDAQIL

Function

Subunit of the replication factor C (RFC) complex which acts during elongation of primed DNA templates by DNA polymerases delta and epsilon, and is necessary for ATP-dependent loading of proliferating cell nuclear antigen (PCNA) onto primed DNA. This subunit binds ATP

Protein Sequence

10 CCPGDGNTVT 20 HCFRGIDVVR 30 NKIKMFAQQK 40 VTLPKGRHKI 50 IILDEADSMT 60 DGAQQALRRT 70 MEIYSKTTRF 80 ALACNASDKI 90 IEPIQSRCAV 100 LRYTKLTDAQ 110 ILARLLNVIE 120 KEKVPYTDDG 130 LEAIIFTAQG 140 DMRQALNNLQ 150 STFSGFGFIN 160 SENVFKVCDE 170 PHPLLVKEMI 180 QHCVSANIDE 190 AYKILAHLWH 200 LGYSPEDIIG 210 NIFRVCKTFQ 220 MAEYLKLEFI 230 KEIGYTHMRV 240 AEGVNSLLQM 250 AGLLARLCQK TVAPVAS

Gene Ontology

Classification GO ID Description
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0003677 DNA binding
Biological Process GO:0006260 DNA replication

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.