Search Results
Overview
| Uniprot ID | A0A8W4FJU4 |
|---|---|
| Protein Name | Heme oxygenase 1 |
| Gene Name | HMOX1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 39 | EFMKNFQKGEVTREG |
Function
Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron
Protein Sequence
10
MEHSQPNSVP
20
QDLSEALKEA
30
TKEVHVQAEN
40
AEFMKNFQKG
50
EVTREGFKLF
60
EEVQELLTQD
70
TKDQRPSQAS
80
DVRKRAGSRV
90
QDSTPVTTPR
100
GKPQLSVLSQ
110
VPLVRWVLTL
120
SFLVATVAMG
LYAM
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Molecular Function | GO:0004392 | heme oxygenase (decyclizing) activity |
| Biological Process | GO:0006788 | heme oxidation |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.