Search Results

Overview

Uniprot ID	A0A8W4FJY5
Protein Name	Tubulin alpha chain
Gene Name	TUBA1B
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
105	PEQLITGKEDAANNY
172	RLSVDYGKKSKLEFS
335	YRGDVVPKDVNAAIA
345	NAAIATIKTKRSIQF
379	VPGGDLAKVQRAVCM
403	AWARLDHKFDLMYAK
410	KFDLMYAKRAFVHWY
69	FSETGAGKHVPRAVF

Function

Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin

Protein Sequence

10 MEGVRVPHHC 20 RECISIHVGQ 30 AGVQIGNACW 40 ELYCLEHGIQ 50 PDGQMPSDKT 60 IGGGDDSFNT 70 FFSETGAGKH 80 VPRAVFVDLE 90 PTVIDEVRTG 100 TYRQLFHPEQ 110 LITGKEDAAN 120 NYARGHYTIG 130 KEIIDLVLDR 140 IRKLADQCTG 150 LQGFLVFHSF 160 GGGTGSGFTS 170 LLMERLSVDY 180 GKKSKLEFSI 190 YPAPQVSTAV 200 VEPYNSILTT 210 HTTLEHSDCA 220 FMVDNEAIYD 230 ICRRNLDIER 240 PTYTNLNRLI 250 SQIVSSITAS 260 LRFDGALNVD 270 LTEFQTNLVP 280 YPRIHFPLAT 290 YAPVISAEKA 300 YHEQLSVAEI 310 TNACFEPANQ 320 MVKCDPRHGK 330 YMACCLLYRG 340 DVVPKDVNAA 350 IATIKTKRSI 360 QFVDWCPTGF 370 KVGINYQPPT 380 VVPGGDLAKV 390 QRAVCMLSNT 400 TAIAEAWARL 410 DHKFDLMYAK 420 RAFVHWYVGE 430 GMEEGEFSEA 440 REDMAALEKD 450 YEEVGVDSVE 460 GEGEEEGEEY

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005874	microtubule
Molecular Function	GO:0005525	GTP binding
Molecular Function	GO:0016787	hydrolase activity
Molecular Function	GO:0005200	structural constituent of cytoskeleton
Biological Process	GO:0007017	microtubule-based process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.