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Overview

Uniprot IDA0A8W4FJY9
Protein Name-
Gene NamePOGLUT3
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
338 WKHYVPIKRNLSDLL
80 RTLSCPTKEPQIAKD

Function

Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C. Can also catalyze the transfer of xylose from UDP-xylose but less efficiently. Specifically targets extracellular EGF repeats of proteins such as NOTCH1, NOTCH3, FBN1, FBN2 and LTBP1. May regulate the transport of NOTCH1 and NOTCH3 to the plasma membrane and thereby the Notch signaling pathway

Protein Sequence

10 PKEIVRIHVP 20 KPLDRNDGTF 30 LMRYRMYETV 40 NEGLKIEVLY 50 GDEHVAQSPY 60 ILKGPVYHEY 70 CECPEEDPQA 80 WQRTLSCPTK 90 EPQIAKDFAS 100 FPSINLQQML 110 NEIPRRFGEE 120 RGAIVHYTIL 130 NNHIYRRSLG 140 KYTDFKMFSD 150 EILLSLARKV 160 LLPDVEFYVN 170 LGDWPLEHRK 180 VNETPGPLPI 190 ISWCGSLDSR 200 DVILPTYDIT 210 HSTLEAMRGV 220 TNDLLSIQGH 230 TGPSWINKTE 240 KAFFRGRDSR 250 EERLQLVQLS 260 KENPQLLDAG 270 ITGYFFFQEK 280 EKELGKAKLI 290 GFFDFFKYKY 300 QVNVDGTVAA 310 YRYPYLMLGD 320 SLVLKQDSPY 330 YEHFYMALKP 340 WKHYVPIKRN 350 LSDLLEKIEW 360 AKEHDEEAKK 370 IAKEGQLTAR 380 DLLQPHRLYC 390 YYYRVLQKYA 400 ERQTSKPEIR 410 DGMELVPQPD 420 DSSSICQCHR KTPLREEL

Gene Ontology

No Gene Ontology data available.

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.