Search Results
Overview
| Uniprot ID | A0A8W4FK22 |
|---|---|
| Protein Name | DNA sliding clamp PCNA |
| Gene Name | PCNA |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 172 | AVVISCAKDGVKFSA |
| 21 | LVQGSILKKVLEALK |
| 22 | VQGSILKKVLEALKD |
| 88 | TSMSKILKCAGNEDI |
Function
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processivity during elongation of the leading strand
Protein Sequence
10
PRRCDSTTMF
20
EARLVQGSIL
30
KKVLEALKDL
40
INEACWDISS
50
SGVNLQSMDS
60
SHVSLVQLTL
70
RSEGFDTYRC
80
DRNLAMGVNL
90
TSMSKILKCA
100
GNEDIITLRA
110
EDNADTLALV
120
FEAPNQEKVS
130
DYEMKLMDLD
140
VEQLGIPEQE
150
YSCVVKMPSG
160
EFARICRDLS
170
HIGDAVVISC
180
AKDGVKFSAS
190
GELGNGNIKL
200
SQTSNVDKEE
210
EAVTIEMNEP
220
VQLTFALRYL
230
NFFTKATPLS
240
PTVTLSMSAD
250
VPLVVEYKIA
260
DMGHLKYYLA
PKIEDEEGS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0030337 | DNA polymerase processivity factor activity |
| Biological Process | GO:0006260 | DNA replication |
| Biological Process | GO:0006275 | regulation of DNA replication |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.