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Overview

Uniprot IDA0A8W4FK55
Protein NameTubulin alpha chain
Gene NameTUBA1B
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
110 PEQLITGKEDAANNY
177 RLSVDYGKKSKLEFS
340 YRGDVVPKDVNAAIA
350 NAAIATIKTKRSIQF
384 VPGGDLAKVQRAVCM
408 AWARLDHKFDLMYAK
415 KFDLMYAKRAFVHWY
74 FSETGAGKHVPRAVF

Function

Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin

Protein Sequence

10 RAGSPRPHFL 20 LSAKSRECIS 30 IHVGQAGVQI 40 GNACWELYCL 50 EHGIQPDGQM 60 PSDKTIGGGD 70 DSFNTFFSET 80 GAGKHVPRAV 90 FVDLEPTVID 100 EVRTGTYRQL 110 FHPEQLITGK 120 EDAANNYARG 130 HYTIGKEIID 140 LVLDRIRKLA 150 DQCTGLQGFL 160 VFHSFGGGTG 170 SGFTSLLMER 180 LSVDYGKKSK 190 LEFSIYPAPQ 200 VSTAVVEPYN 210 SILTTHTTLE 220 HSDCAFMVDN 230 EAIYDICRRN 240 LDIERPTYTN 250 LNRLISQIVS 260 SITASLRFDG 270 ALNVDLTEFQ 280 TNLVPYPRIH 290 FPLATYAPVI 300 SAEKAYHEQL 310 SVAEITNACF 320 EPANQMVKCD 330 PRHGKYMACC 340 LLYRGDVVPK 350 DVNAAIATIK 360 TKRSIQFVDW 370 CPTGFKVGIN 380 YQPPTVVPGG 390 DLAKVQRAVC 400 MLSNTTAIAE 410 AWARLDHKFD 420 LMYAKRAFVH 430 WYVGEGMEEG 440 EFSEAREDMA 450 ALEKDYEEVG 460 VDSVEGEGEE EGEEY

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005874 microtubule
Molecular Function GO:0005525 GTP binding
Molecular Function GO:0016787 hydrolase activity
Molecular Function GO:0005200 structural constituent of cytoskeleton
Biological Process GO:0007017 microtubule-based process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.