Search Results

Overview

Uniprot IDA0A8W4FL25
Protein Name-
Gene NameTUBA1B
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
174 FSETGAGKHVPRAVF
210 PEQLITGKEDAANNY
277 RLSVDYGKKSKLEFS
440 YRGDVVPKDVNAAIA
450 NAAIATIKTKRSIQF
484 VPGGDLAKVQRAVCM
508 AWARLDHKFDLMYAK
515 KFDLMYAKRAFVHWY

Function

Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin

Protein Sequence

10 MKSRARAEGG 20 SRYWRTAGAR 30 KWEATLFSSR 40 TLEGDCRAPA 50 LLHCGWGSPL 60 AFNSWARCPE 70 TLQSFPACSH 80 PPLLPPTSGG 90 RARGLSPREG 100 ARHKTSVLLL 110 SPLIGFIFFF 120 PTFSQRECIS 130 IHVGQAGVQI 140 GNACWELYCL 150 EHGIQPDGQM 160 PSDKTIGGGD 170 DSFNTFFSET 180 GAGKHVPRAV 190 FVDLEPTVID 200 EVRTGTYRQL 210 FHPEQLITGK 220 EDAANNYARG 230 HYTIGKEIID 240 LVLDRIRKLA 250 DQCTGLQGFL 260 VFHSFGGGTG 270 SGFTSLLMER 280 LSVDYGKKSK 290 LEFSIYPAPQ 300 VSTAVVEPYN 310 SILTTHTTLE 320 HSDCAFMVDN 330 EAIYDICRRN 340 LDIERPTYTN 350 LNRLISQIVS 360 SITASLRFDG 370 ALNVDLTEFQ 380 TNLVPYPRIH 390 FPLATYAPVI 400 SAEKAYHEQL 410 SVAEITNACF 420 EPANQMVKCD 430 PRHGKYMACC 440 LLYRGDVVPK 450 DVNAAIATIK 460 TKRSIQFVDW 470 CPTGFKVGIN 480 YQPPTVVPGG 490 DLAKVQRAVC 500 MLSNTTAIAE 510 AWARLDHKFD 520 LMYAKRAFVH 530 WYVGEGMEEG 540 EFSEAREDMA 550 ALEKDYEEVG 560 VDSVEGEGEE EGEEY

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005929 cilium
Cellular Component GO:0005881 cytoplasmic microtubule
Molecular Function GO:0003725 double-stranded RNA binding
Molecular Function GO:0005525 GTP binding
Molecular Function GO:0003924 GTPase activity
Molecular Function GO:0005200 structural constituent of cytoskeleton
Molecular Function GO:0031625 ubiquitin protein ligase binding
Biological Process GO:0000226 microtubule cytoskeleton organization

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.