Search Results
Overview
| Uniprot ID | A0A8W4FL76 |
|---|---|
| Protein Name | Translin |
| Gene Name | TSN |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 205 | LSIRGFNKETVAACS |
| 62 | KTHLTSLKTKFPAEQ |
| 64 | HLTSLKTKFPAEQYY |
Function
DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots
Protein Sequence
10
FPASRLLQEI
20
RKVVQSLEQT
30
AREILTLLQG
40
VHQGAGFQDI
50
PKRCLKAREH
60
FGTVKTHLTS
70
LKTKFPAEQY
80
YRFHEHWRFV
90
LQRLVFLAAF
100
VVYLESETLV
110
TREAVTEILG
120
IEPDREKGFH
130
LDVEDYLSGV
140
LILASELSRL
150
SVNSVTAGDY
160
ARPLHISTFI
170
NELDSGFRLL
180
NLKNDSLRKR
190
YDGLKYDVKK
200
VEEVVYDLSI
210
RGFNKETVAA
CSEK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0004519 | endonuclease activity |
| Molecular Function | GO:0016787 | hydrolase activity |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0043565 | sequence-specific DNA binding |
| Molecular Function | GO:0003697 | single-stranded DNA binding |
| Biological Process | GO:0016070 | RNA metabolic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.