Search Results
Overview
| Uniprot ID | A0A8W4FM07 |
|---|---|
| Protein Name | Cleavage and polyadenylation specificity factor subunit 4 |
| Gene Name | CPSF4 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 69 | GEKTVVCKHWLRGLC |
Function
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U)
Protein Sequence
10
MQEIIASVDH
20
IKFDLEIAVE
30
QQLGAQPLPF
40
PGMDKSGAAV
50
CEFFLKAACG
60
KGGMCPFRHI
70
SGEKTVVCKH
80
WLRGLCKKGD
90
QCEFLHEYDM
100
TKMPECYFYS
110
KFGPLCRHRH
120
TRRVICVNYL
130
VGFCPEGPSC
140
KFMHPRFELP
150
MGTTEQPPLP
160
QQTQPPAKRA
170
PQVIGVMQSQ
180
NSSAGNRGPR
190
PLEQVTCYKC
200
GEKGHYANRC
210
TKGHLAFLSG
Q
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0031124 | mRNA 3'-end processing |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.