Search Results
Overview
| Uniprot ID | A0A8W4FMQ0 |
|---|---|
| Protein Name | U5 small nuclear ribonucleoprotein TSSC4 |
| Gene Name | TSSC4 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 257 | SRDHFRSKGHGPEAP |
Function
Protein associated with the U5 snRNP, during its maturation and its post-splicing recycling and which is required for spliceosomal tri-snRNP complex assembly in the nucleus. Has a molecular sequestering activity and transiently hinders SNRNP200 binding sites for constitutive splicing factors that intervene later during the assembly of the spliceosome and splicing. Together with its molecular sequestering activity, may also function as a molecular adapter and placeholder, coordinating the assembly of the U5 snRNP and its association with the U4/U6 di-snRNP
Protein Sequence
10
GAPRAPPGPP
20
GAVVQPFHLR
30
GTSPTFSQRS
40
HDIFDHLEGA
50
AGRALPSAAP
60
AGPGHSGGFK
70
LPPLPSRRPP
80
AGARGRATQS
90
PAPPRAPPVP
100
DYVAHPERWT
110
KYSLEDVAEA
120
SEQSNRAAAL
130
AFLGPQSLAA
140
PGDYVPSFNQ
150
DPSSCGEGRV
160
VFTKPARTSE
170
ARPERKRGLR
180
KAGEPGRAAP
190
GSPGTAGGGD
200
GPVELAHLAG
210
PGSPEAAEEG
220
SGPRGGLVEV
230
AVPEGLAPPG
240
AAAGPSPVET
250
VGFHGSKKRS
260
RDHFRSKGHG
PEAPGGAEA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005681 | spliceosomal complex |
| Biological Process | GO:0006397 | mRNA processing |
| Biological Process | GO:0008380 | RNA splicing |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.