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Overview

Uniprot IDA0A8W4FPM5
Protein NameOCIA domain-containing protein 1
Gene NameOCIAD1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
170 IEESPKRKNVTYEEL
69 AGKLSYVKTCQEKFK
74 YVKTCQEKFKNLENS
76 KTCQEKFKNLENSPL

Function

Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes

Protein Sequence

10 MSGRAEFREP 20 NAEVPRPIPP 30 VPLAATSMLI 40 TQGLISKGIL 50 SSHPRYGSIP 60 KLIFACIMGY 70 FAGKLSYVKT 80 CQEKFKNLEN 90 SPLGEALRSG 100 QARRSSPTGH 110 YSQKSRYDSN 120 VSGHSSFATS 130 PAADNIEKEM 140 LPHYEPIPFS 150 ASMNESAPTG 160 ITDHIAQGPD 170 PNIEESPKRK 180 NVTYEELRNK 190 NRESYEVTLT 200 HKTDPSVRPM 210 QERMPKKEVK 220 VNKYGDTWDE

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005768 endosome
Biological Process GO:2000736 regulation of stem cell differentiation

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.