Search Results
Overview
| Uniprot ID | A0A8W4FQE3 |
|---|---|
| Protein Name | DNA sliding clamp PCNA |
| Gene Name | PCNA |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 175 | AVVISCAKDGVKFSA |
| 24 | LVQGSILKKVLEALK |
| 25 | VQGSILKKVLEALKD |
| 91 | TSMSKILKCAGNEDI |
Function
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processivity during elongation of the leading strand
Protein Sequence
10
MKGPRRCDST
20
TMFEARLVQG
30
SILKKVLEAL
40
KDLINEACWD
50
ISSSGVNLQS
60
MDSSHVSLVQ
70
LTLRSEGFDT
80
YRCDRNLAMG
90
VNLTSMSKIL
100
KCAGNEDIIT
110
LRAEDNADTL
120
ALVFEAPNQE
130
KVSDYEMKLM
140
DLDVEQLGIP
150
EQEYSCVVKM
160
PSGEFARICR
170
DLSHIGDAVV
180
ISCAKDGVKF
190
SASGELGNGN
200
IKLSQTSNVD
210
KEEEAVTIEM
220
NEPVQLTFAL
230
RYLNFFTKAT
240
PLSPTVTLSM
250
SADVPLVVEY
260
KIADMGHLKY
270
YLAPKIEDEE
GS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0043626 | PCNA complex |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0030337 | DNA polymerase processivity factor activity |
| Biological Process | GO:0006272 | leading strand elongation |
| Biological Process | GO:0006298 | mismatch repair |
| Biological Process | GO:0006275 | regulation of DNA replication |
| Biological Process | GO:0019985 | translesion synthesis |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.