Search Results

Overview

Uniprot IDA0A8W4FR34
Protein NameU6 snRNA-associated Sm-like protein LSm4
Gene NameLSM4
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
52 CTSRDGDKFWRMPEC
67 YIRGSTIKYLRIPDE

Function

Binds specifically to the 3'-terminal U-tract of U6 snRNA

Protein Sequence

10 MLPLSLLKTA 20 QNHPMLVELK 30 NGETYNGHLV 40 SCDNWMNINL 50 REVICTSRDG 60 DKFWRMPECY 70 IRGSTIKYLR 80 IPDEIIDMVK 90 EEVVAKGRGR 100 GGLQQQKQQK 110 GRGMGGAGRG 120 VFGGRGRGGI 130 PGTGRGQPEK KPGRQAGKQ

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005829 cytosol
Cellular Component GO:0120115 Lsm2-8 complex
Cellular Component GO:0016020 membrane
Cellular Component GO:0000932 P-body
Cellular Component GO:0097526 spliceosomal tri-snRNP complex
Cellular Component GO:0071005 U2-type precatalytic spliceosome
Cellular Component GO:0046540 U4/U6 x U5 tri-snRNP complex
Cellular Component GO:0005688 U6 snRNP
Molecular Function GO:0042731 PH domain binding
Molecular Function GO:0017070 U6 snRNA binding
Biological Process GO:0000956 nuclear-transcribed mRNA catabolic process
Biological Process GO:0033962 P-body assembly
Biological Process GO:0000387 spliceosomal snRNP assembly

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.