Search Results
Overview
| Uniprot ID | A0A8X9AEQ6 |
|---|---|
| Protein Name | Actin-related protein 2/3 complex subunit 5 |
| Gene Name | ARPC5 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 13 | VSSARFRKVDVDEYD |
| 3 | *****MSKNTVSSAR |
| 70 | KNPPINTKSQAVKDR |
| 90 | LKVLISFKANDIEKA |
| 96 | FKANDIEKAVQSLDK |
Function
Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development
Protein Sequence
10
MSKNTVSSAR
20
FRKVDVDEYD
30
ENKFVDEEDG
40
GDGQAGPDEG
50
EVDSCLRHSF
60
TGNMTAALQA
70
ALKNPPINTK
80
SQAVKDRAGS
90
IVLKVLISFK
100
ANDIEKAVQS
110
LDKNGVDLLM
120
KYIYKGFESP
130
SDNSSAMLLQ
140
WHEKALAAGG
150
VGSIVRVLTA
RKTV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005885 | Arp2/3 protein complex |
| Cellular Component | GO:0030863 | cortical cytoskeleton |
| Cellular Component | GO:0030027 | lamellipodium |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0051015 | actin filament binding |
| Molecular Function | GO:0030674 | protein-macromolecule adaptor activity |
| Molecular Function | GO:0005200 | structural constituent of cytoskeleton |
| Biological Process | GO:0034314 | Arp2/3 complex-mediated actin nucleation |
| Biological Process | GO:0016477 | cell migration |
| Biological Process | GO:0030833 | regulation of actin filament polymerization |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.