Search Results

Overview

Uniprot ID	A0A900QKV7
Protein Name	Tubulin alpha chain
Gene Name	TUBA1B
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
101	PEQLITGKEDAANNY
168	RLSVDYGKKSKLEFS
331	YRGDVVPKDVNAAIA
341	NAAIATIKTKRSIQF
375	VPGGDLAKVQRAVCM
399	AWARLDHKFDLMYAK
406	KFDLMYAKRAFVHWY
65	FSETGAGKHVPRAVF

Function

Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin

Protein Sequence

10 LFCLRNRECI 20 SIHVGQAGVQ 30 IGNACWELYC 40 LEHGIQPDGQ 50 MPSDKTIGGG 60 DDSFNTFFSE 70 TGAGKHVPRA 80 VFVDLEPTVI 90 DEVRTGTYRQ 100 LFHPEQLITG 110 KEDAANNYAR 120 GHYTIGKEII 130 DLVLDRIRKL 140 ADQCTGLQGF 150 LVFHSFGGGT 160 GSGFTSLLME 170 RLSVDYGKKS 180 KLEFSIYPAP 190 QVSTAVVEPY 200 NSILTTHTTL 210 EHSDCAFMVD 220 NEAIYDICRR 230 NLDIERPTYT 240 NLNRLISQIV 250 SSITASLRFD 260 GALNVDLTEF 270 QTNLVPYPRI 280 HFPLATYAPV 290 ISAEKAYHEQ 300 LSVAEITNAC 310 FEPANQMVKC 320 DPRHGKYMAC 330 CLLYRGDVVP 340 KDVNAAIATI 350 KTKRSIQFVD 360 WCPTGFKVGI 370 NYQPPTVVPG 380 GDLAKVQRAV 390 CMLSNTTAIA 400 EAWARLDHKF 410 DLMYAKRAFV 420 HWYVGEGMEE 430 GEFSEAREDM 440 AALEKDYEEV 450 GVDSVEGEGE EEGEEY

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005874	microtubule
Molecular Function	GO:0005525	GTP binding
Molecular Function	GO:0016787	hydrolase activity
Molecular Function	GO:0005200	structural constituent of cytoskeleton
Biological Process	GO:0007017	microtubule-based process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.