Search Results
Overview
| Uniprot ID | A1L108 |
|---|---|
| Protein Name | Actin-related protein 2/3 complex subunit 5-like protein |
| Gene Name | Arpc5l |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 69 | RNSPINTKNQAVKER |
Function
May function as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks
Protein Sequence
10
MARNTLSSRF
20
RRVDIDEFDE
30
NKFVDEHEEA
40
AAASGEPGPD
50
PCEVDGLLRQ
60
GDMLRAFHAA
70
LRNSPINTKN
80
QAVKERAQGI
90
VLKVLTNFKS
100
SEIEQAVQSL
110
DRNGIDLLMK
120
YIYKGFEKPT
130
ENSSAVLLQW
140
HEKALAVGGL
150
GSIIRVLTAR
KTV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005885 | Arp2/3 protein complex |
| Cellular Component | GO:0030863 | cortical cytoskeleton |
| Cellular Component | GO:0098978 | glutamatergic synapse |
| Cellular Component | GO:0045202 | synapse |
| Molecular Function | GO:0003779 | actin binding |
| Molecular Function | GO:0030674 | protein-macromolecule adaptor activity |
| Biological Process | GO:0034314 | Arp2/3 complex-mediated actin nucleation |
| Biological Process | GO:0016477 | cell migration |
| Biological Process | GO:0030833 | regulation of actin filament polymerization |
Reference
[1] Yao Y, Bade R, Li G, Zhang A, Zhao H et al.. Global-Scale Profiling of Differential Expressed Lysine-Lactylated Proteins in the Cerebral Endothelium of Cerebral Ischemia-Reperfusion Injury Rats.. Cell Mol Neurobiol 43(5):1989-2004. 2023 Jul. PMID: 36030297.
[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.