Search Results
Overview
| Uniprot ID | A4D1S5 |
|---|---|
| Protein Name | Ras-related protein Rab-19 |
| Gene Name | RAB19 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 177 | EVFVLMAKELIARNS |
Function
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion
Protein Sequence
10
MHFSSSARAA
20
DENFDYLFKI
30
ILIGDSNVGK
40
TCVVQHFKSG
50
VYTETQQNTI
60
GVDFTVRSLD
70
IDGKKVKMQV
80
WDTAGQERFR
90
TITQSYYRSA
100
HAAIIAYDLT
110
RRSTFESIPH
120
WIHEIEKYGA
130
ANVVIMLIGN
140
KCDLWEKRHV
150
LFEDACTLAE
160
KYGLLAVLET
170
SAKESKNIEE
180
VFVLMAKELI
190
ARNSLHLYGE
200
SALNGLPLDS
210
SPVLMAQGPS
EKTHCTC
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0012505 | endomembrane system |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0003925 | G protein activity |
| Molecular Function | GO:0005525 | GTP binding |
| Molecular Function | GO:0003924 | GTPase activity |
| Molecular Function | GO:0046872 | metal ion binding |
| Biological Process | GO:0000045 | autophagosome assembly |
| Biological Process | GO:0006886 | intracellular protein transport |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.