Search Results
Overview
| Uniprot ID | A5A757 |
|---|---|
| Protein Name | Inhibitor of nuclear factor kappa-B kinase subunit beta |
| Gene Name | IKBKB |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 621 | KTVVCKQKALELLPR |
Function
No function data available.
Protein Sequence
10
MSWSPSLTTQ
20
TCGAWEMKER
30
LGTGGFGNVI
40
RWHNQETGEQ
50
IAIKQCRQEL
60
SPRNRERWCL
70
EIQIMRRLNH
80
PNVVAARDVP
90
EGMQNLAPND
100
LPLLAMEYCQ
110
GGDLRKYLNQ
120
FENCCGLREG
130
AILTLLSDIA
140
SALRYLHENR
150
IIHRDLKPEN
160
IVLQQGEQRL
170
IHKIIDLGYA
180
KELDQGSLCT
190
SFVGTLQYLA
200
PELLEQQKYT
210
VTVDYWSFGT
220
LAFECITGFR
230
PFLPNWQPVQ
240
WHSKVRQKSE
250
MDIVVSEDLN
260
GTVKFSSSLP
270
YPNNLNSVLA
280
QRLEKWLQLM
290
LMWHPRQRGT
300
DPTYGPNGCF
310
KALDDILTLK
320
LVHILNMVTG
330
TIHTYPVTED
340
ESLQSLKARI
350
RQDTGILEEA
360
QELLQEAGLA
370
LIPDKPAAQC
380
ISDGKLNEGR
390
TLDMDLVFLF
400
DNSRVTYDTQ
410
ISPRPQPESV
420
SCILQEPKRN
430
LPFFQLRKVW
440
GQVWHSIQAL
450
KEDCSRLQQG
460
QRAAMMNLLR
470
NNSCLSKMKN
480
SMASMSQQLK
490
AKLDFFKTSI
500
QIDLEKYSEQ
510
TEFGITSDKL
520
LLAWREMEQA
530
VELCGRENEV
540
KHLVERMMAL
550
QTDIVDLQRS
560
PMGRKQGGTL
570
DDLEEQAREL
580
YRRLREKPRD
590
QRTDGDSQEM
600
VRLLLQAIQG
610
FEKKVRVIYT
620
QLSKTVVCKQ
630
KALELLPRVE
640
EVVSLMNEDE
650
KTVVRLQEKR
660
QKELWNLLKI
670
ACSKVRGPVS
680
GSPDSMNASR
690
LSHPSQLMSQ
700
PCPAPDSLPE
710
AIKKSEDLVA
720
EAHSLCAQLE
730
NVLQDTMKEQ
740
DQSLKSLDWS
750
WLQVEEEQNS
LEQAS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0008385 | IkappaB kinase complex |
| Cellular Component | GO:0045121 | membrane raft |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0008384 | IkappaB kinase activity |
| Molecular Function | GO:0046982 | protein heterodimerization activity |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Molecular Function | GO:0019901 | protein kinase binding |
| Molecular Function | GO:0097110 | scaffold protein binding |
| Molecular Function | GO:1990459 | transferrin receptor binding |
| Biological Process | GO:0070498 | interleukin-1-mediated signaling pathway |
| Biological Process | GO:1903347 | negative regulation of bicellular tight junction assembly |
| Biological Process | GO:1900016 | negative regulation of cytokine production involved in inflammatory response |
| Biological Process | GO:0043123 | positive regulation of canonical NF-kappaB signal transduction |
| Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II |
| Biological Process | GO:0072659 | protein localization to plasma membrane |
| Biological Process | GO:0051604 | protein maturation |
| Biological Process | GO:1903140 | regulation of establishment of endothelial barrier |
| Biological Process | GO:0033209 | tumor necrosis factor-mediated signaling pathway |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.