Search Results
Overview
| Uniprot ID | A5A779 |
|---|---|
| Protein Name | Geranylgeranyl transferase type-2 subunit alpha |
| Gene Name | RABGGTA |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 335 | QKECVLLKGRQEGWC |
Function
Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A
Protein Sequence
10
MHGRLKVKTS
20
EEQAEAKRLE
30
REQKLKLYQT
40
ATQTVFQKRQ
50
AGELDESVLE
60
LTSQILGANP
70
DFATLWNCRR
80
EVLQRLEVQK
90
SPEELAALVK
100
AELGFLESCL
110
RVNPKSYGTW
120
HHRCWLLGRL
130
PEPNWARELE
140
LCARFLEVDE
150
RNFHCWDYRR
160
FVASQAAVPP
170
AEELAFTDSL
180
ITRNFSNYSS
190
WHYRSCLLPQ
200
LHPQPDSGPQ
210
GRLPEDVLLK
220
ELELVQNAFF
230
TDPNDQSAWF
240
YHRWLLGRAD
250
PQDALRCLHV
260
SRDEACLTVS
270
FSRPLLVGPS
280
TETLLLMVNE
290
SPLSVEWRTP
300
DGRNRPSHVW
310
LCDLPAASLN
320
DHLPQHTFRV
330
IWTAGNAQKE
340
CVLLKGRQEG
350
WCRDSATDEQ
360
LFRCELSVEK
370
STVLQSELES
380
CKELQELEPE
390
NKWCLLTIIL
400
LMRALDPLLY
410
EKETLQYFQT
420
LKAVDPMRAA
430
YLDDLRSKFL
440
LENSVLKMEY
450
ADVRVLHLGH
460
KDLTVLCHLE
470
QLLLVTHLDL
480
SHNRLRALPP
490
ALAALRCLEV
500
LQANDNAIES
510
LDGVTNLPRL
520
QELSLCNNRL
530
QQPAVLQPLA
540
SCPRLVLLNL
550
QDNPLCQAVG
560
ISEHLAELLP
SVSSILT
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005968 | Rab-protein geranylgeranyltransferase complex |
| Molecular Function | GO:0004663 | Rab geranylgeranyltransferase activity |
| Molecular Function | GO:0031267 | small GTPase binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0006888 | endoplasmic reticulum to Golgi vesicle-mediated transport |
| Biological Process | GO:0018344 | protein geranylgeranylation |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.