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Overview

Uniprot IDA5A8V8
Protein NameU6 snRNA-associated Sm-like protein LSm2
Gene NameLSM2
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
13 FFKSLVGKDVVVELK

Function

Binds specifically to the 3'-terminal U-tract of U6 snRNA

Protein Sequence

10 MLFYSFFKSL 20 VGKDVVVELK 30 NDLSICGTLH 40 SVDQYLNIKL 50 TDISVTDPEK 60 YPHMLSVKNC 70 FIRGSVVRYV 80 QLPADEVDTQ 90 LLQDAARKEA LQQKQ

Gene Ontology

Classification GO ID Description
Cellular Component GO:0071013 catalytic step 2 spliceosome
Cellular Component GO:1990726 Lsm1-7-Pat1 complex
Cellular Component GO:0000932 P-body
Cellular Component GO:0071011 precatalytic spliceosome
Cellular Component GO:0046540 U4/U6 x U5 tri-snRNP complex
Cellular Component GO:0005688 U6 snRNP
Molecular Function GO:0003723 RNA binding
Biological Process GO:0000398 mRNA splicing, via spliceosome

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.