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Overview

Uniprot IDA5GFN6
Protein NamemRNA export factor
Gene NameRAE1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
108 VFTASCDKTAKMWDL
222 HRCVAIFKDKQNKPT
350 EFYNPQKKNYIFLRN

Function

Plays a role in mitotic bipolar spindle formation. Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton

Protein Sequence

10 MSLFGTTSGF 20 GTSGTSMFGS 30 TTTDNHNPMK 40 DIEVTSSPDD 50 SIGCLSFSPP 60 TLPGNFLIAG 70 SWANDVRCWE 80 VQDSGQTIPK 90 AQQMHTGPVL 100 DVCWSDDGSK 110 VFTASCDKTA 120 KMWDLNSNQA 130 IQIAQHDAPV 140 KTIHWIKAPN 150 YSCVMTGSWD 160 KTLKFWDTRS 170 SNPMMVLQLP 180 ERCYCADVIY 190 PMAVVATAER 200 GLIVYQLENQ 210 PSEFRRIESP 220 LKHQHRCVAI 230 FKDKQNKPTG 240 FALGSIEGRV 250 AIHYINPPNP 260 AKDNFTFKCH 270 RSNGTNTSAP 280 QDIYAVNGIA 290 FHPVHGTLAT 300 VGSDGRFSFW 310 DKDARTKLKT 320 SEQLDQPISA 330 CCFNHNGNIF 340 AYASSYDWSK 350 GHEFYNPQKK 360 NYIFLRNAAE ELKPRNKK

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0001650 fibrillar center
Cellular Component GO:0097431 mitotic spindle pole
Cellular Component GO:0005643 nuclear pore
Cellular Component GO:0005654 nucleoplasm
Molecular Function GO:0003723 RNA binding
Molecular Function GO:0043130 ubiquitin binding
Biological Process GO:0051301 cell division
Biological Process GO:0060236 regulation of mitotic spindle organization
Biological Process GO:0006405 RNA export from nucleus
Biological Process GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.