Search Results
Overview
| Uniprot ID | A5GFQ9 |
|---|---|
| Protein Name | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit |
| Gene Name | PPP2R5D |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 102 | SKNRELQKLPALKDS |
| 121 | REELFIQKLRQCCVL |
| 489 | DDCTQQYKAEKQKGR |
| 572 | EKVLLRRKSELPQDV |
| 583 | PQDVYTIKALEAHKR |
| 71 | PPPTQLSKIKYSGGP |
| 73 | PTQLSKIKYSGGPQI |
Function
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment
Protein Sequence
10
MPYKLKKEKE
20
PPKLAKSTAK
30
PSSSSKDGAG
40
ESAEEAQPQP
50
QPQPQPPPQP
60
QPPSSNKRPS
70
NSTPPPTQLS
80
KIKYSGGPQI
90
VKKERRQSSS
100
RFNLSKNREL
110
QKLPALKDSP
120
TQEREELFIQ
130
KLRQCCVLFD
140
FVSDPLSDLK
150
FKEVKRAGLN
160
EMVEYITHSR
170
DVVTEAIYPE
180
AVTMFSVNLF
190
RTLPPSSNPT
200
GAEFDPEEDE
210
PTLEAAWPHL
220
QLVYEFFLRF
230
LESPDFQPNI
240
AKKYIDQKFV
250
LALLDLFDSE
260
DPRERDFLKT
270
ILHRIYGKFL
280
GLRAYIRRQI
290
NHIFYRFIYE
300
TEHHNGIAEL
310
LEILGSIING
320
FALPLKEEHK
330
MFLIRVLLPL
340
HKVKSLSVYH
350
PQLAYCVVQF
360
LEKESSLTEP
370
VIVGLLKFWP
380
KTHSPKEVMF
390
LNELEEILDV
400
IEPSEFSKVM
410
EPLFRQLAKC
420
VSSPHFQVAE
430
RALYYWNNEY
440
IMSLISDNAA
450
RVLPIMFPAL
460
YRNSKSHWNK
470
TIHGLIYNAL
480
KLFMEMNQKL
490
FDDCTQQYKA
500
EKQKGRFRMK
510
EREEMWQKIE
520
ELARLNPQYP
530
MFRAPPPLPP
540
VYSMETETPT
550
AEDIQLLKRT
560
VETEAVQMLK
570
DIKKEKVLLR
580
RKSELPQDVY
590
TIKALEAHKR
600
AEEFLTASQE
AL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0000159 | protein phosphatase type 2A complex |
| Molecular Function | GO:0072542 | protein phosphatase activator activity |
| Biological Process | GO:0051177 | meiotic sister chromatid cohesion |
| Biological Process | GO:0007165 | signal transduction |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.