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Overview

Uniprot IDA5GFU5
Protein NameGuanine nucleotide-binding protein G(s) subunit alpha
Gene NameGNAS
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
8 MGCLGNSKTEDQRNE

Function

Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs)

Protein Sequence

10 MGCLGNSKTE 20 DQRNEEKAQR 30 EANKKIEKQL 40 QKDKQVYRAT 50 HRLLLLGAGE 60 SGKSTIVKQM 70 RILHVNGFNG 80 EGGEEDPQAA 90 RSNSDGEKAT 100 KVQDIKNNLK 110 EAIETIVAAM 120 SNLVPPVELA 130 NPENQFRVDY 140 ILSVMNVPDF 150 DFPPEFYEHA 160 KALWEDEGVR 170 ACYERSNEYQ 180 LIDCAQYFLD 190 KIDVIKQADY 200 VPSDQDLLRC 210 RVLTSGIFET 220 KFQVDKVNFH 230 MFDVGGQRDE 240 RRKWIQCFND 250 VTAIIFVVAS 260 SSYNMVIRED 270 NQTNRLQEAL 280 NLFKSIWNNR 290 WLRTISVILF 300 LNKQDLLAEK 310 VLAGKSKIED 320 YFPEFARYTT 330 PEDATPEPGE 340 DPRVTRAKYF 350 IRDEFLRIST 360 ASGDGRHYCY 370 PHFTCAVDTE 380 NIRRVFNDCR 390 DIIQRMHLRQ YELL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005834 heterotrimeric G-protein complex
Molecular Function GO:0031683 G-protein beta/gamma-subunit complex binding
Molecular Function GO:0005525 GTP binding
Molecular Function GO:0003924 GTPase activity
Molecular Function GO:0046872 metal ion binding
Biological Process GO:0007186 G protein-coupled receptor signaling pathway

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.