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Overview

Uniprot IDA5GFU7
Protein NameGuanine nucleotide-binding protein G(s) subunit alpha
Gene NameGNAS
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
8 MGCLGNSKTEDQRNE

Function

Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs)

Protein Sequence

10 MGCLGNSKTE 20 DQRNEEKAQR 30 EANKKIEKQL 40 QKDKQVYRAT 50 HRLLLLGAGE 60 SGKSTIVKQM 70 RILHVNGFNG 80 EGGEEDPQAA 90 RSNSDGSEKA 100 TKVQDIKNNL 110 KEAIETIVAA 120 MSNLVPPVEL 130 ANPENQFRVD 140 YILSVMNVPD 150 FDFPPEFYEH 160 AKALWEDEGV 170 RACYERSNEY 180 QLIDCAQYFL 190 DKIDVIKQAD 200 YVPSDQDLLR 210 CRVLTSGIFE 220 TKFQVDKVNF 230 HMFDVGGQRD 240 ERRKWIQCFN 250 DVTAIIFVVA 260 SSSYNMVIRE 270 DNQTNRLQEA 280 LNLFKSIWNN 290 RWLRTISVIL 300 FLNKQDLLAE 310 KVLAGKSKIE 320 DYFPEFARYT 330 TPEDATPEPG 340 EDPRVTRAKY 350 FIRDEFLRIS 360 TASGDGRHYC 370 YPHFTCAVDT 380 ENIRRVFNDC 390 RDIIQRMHLR QYELL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005834 heterotrimeric G-protein complex
Molecular Function GO:0031683 G-protein beta/gamma-subunit complex binding
Molecular Function GO:0005525 GTP binding
Molecular Function GO:0003924 GTPase activity
Molecular Function GO:0046872 metal ion binding
Biological Process GO:0007186 G protein-coupled receptor signaling pathway

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.