Search Results
Overview
| Uniprot ID | A5GFW3 |
|---|---|
| Protein Name | Cleavage stimulation factor subunit 1 |
| Gene Name | CSTF1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 319 | AIFSKNSKYILSSGK |
Function
One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA
Protein Sequence
10
MYRTKVGLKD
20
RQQLYKLIIS
30
QLLYDGYISI
40
ANGLINEIKP
50
QSVCAPSEQL
60
LHLIKLGMEN
70
DDTAVQYAIG
80
RSDTVAPGTG
90
IDLEFDADVQ
100
TMSPEASEYE
110
TCYVTSHKGP
120
CRVATYSRDG
130
QLIATGSADA
140
SIKILDTERM
150
LAKSAMPIEV
160
MMNETAQQNM
170
ENHPVIRTLY
180
DHVDEVTCLA
190
FHPTEQILAS
200
GSRDYTLKLF
210
DYSKPSAKRA
220
FKYIQEAEML
230
RSISFHPSGD
240
FILVGTQHPT
250
LRLYDINTFQ
260
CFVSCNPQDQ
270
HTDAICSVNY
280
NPSANMYVTG
290
SKDGCIKLWD
300
GVSNRCITTF
310
EKAHDGAEVC
320
SAIFSKNSKY
330
ILSSGKDSVA
340
KLWEISTGRT
350
LVRYTGAGLS
360
GRQVHRTQAV
370
FNHTEDYVLL
380
PDERTISLCC
390
WDSRTAERRN
400
LLSLGHNNIV
410
RCIVHSPTNP
420
GFMTCSDDFR
430
ARFWYRRSTT
D
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005848 | mRNA cleavage stimulating factor complex |
| Cellular Component | GO:0005654 | nucleoplasm |
| Biological Process | GO:0031124 | mRNA 3'-end processing |
| Biological Process | GO:0031440 | regulation of mRNA 3'-end processing |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.