Search Results
Overview
| Uniprot ID | A5GFZ5 |
|---|---|
| Protein Name | Dolichol-phosphate mannosyltransferase subunit 1 |
| Gene Name | DPM1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 196 | YRKEVLQKLIEKCVS |
| 200 | VLQKLIEKCVSKGYV |
| 85 | VKIYGSDKILLRPRE |
Function
Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; catalytic subunit of the dolichol-phosphate mannose (DPM) synthase complex
Protein Sequence
10
MASEEASRNS
20
RSRWEPEGRF
30
PRQDKYSVLL
40
PTYNERENLP
50
LIVWLLVKSF
60
SESGINYEII
70
IIDDGSPDGT
80
RDIAEQLVKI
90
YGSDKILLRP
100
REKKLGLGTA
110
YIHGMKHATG
120
NYIIIMDADL
130
SHHPKFIPEF
140
IRKQKEGNFD
150
IVSGTRYKGN
160
GGVYGWDLKR
170
KIISRGANFI
180
TQILLRPGAS
190
DLTGSFRLYR
200
KEVLQKLIEK
210
CVSKGYVFQM
220
EMIVRARQLN
230
YTIGEVPISF
240
VDRVYGESKL
250
GGNEIVSFLK
GLLTLFATT
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0033185 | dolichol-phosphate-mannose synthase complex |
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Molecular Function | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity |
| Molecular Function | GO:0046872 | metal ion binding |
| Biological Process | GO:0180047 | dolichol phosphate mannose biosynthetic process |
| Biological Process | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process |
| Biological Process | GO:0006506 | GPI anchor biosynthetic process |
| Biological Process | GO:0035269 | protein O-linked glycosylation via mannose |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.