Search Results
Overview
| Uniprot ID | A6NDY0 |
|---|---|
| Protein Name | Embryonic polyadenylate-binding protein 2 |
| Gene Name | PABPN1L |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 182 | RVTILCDKFSGHPKG |
Function
Binds the poly(A) tail of mRNA
Protein Sequence
10
MWPFPSRSLF
20
PPPTQAWLQT
30
VSSDPEAQGW
40
GAWNETKEIL
50
GPEGGEGKEE
60
KEEEEDAEED
70
QDGDAGFLLS
80
LLEQENLAEC
90
PLPDQELEAI
100
KMKVCAMEQA
110
EGTPRPPGVQ
120
QQAEEEEGTA
130
AGQLLSPETV
140
GCPLSGTPEE
150
KVEADHRSVY
160
VGNVDYGGSA
170
EELEAHFSRC
180
GEVHRVTILC
190
DKFSGHPKGY
200
AYIEFATKGS
210
VQAAVELDQS
220
LFRGRVIKVL
230
PKRTNFPGIS
240
STDRGGLRGH
250
PGSRGAPFPH
260
SGLQGRPRLR
270
PQGQNRARGK
FSPWFSPY
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Molecular Function | GO:0008143 | poly(A) binding |
| Biological Process | GO:0000288 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay |
Reference
[1] Yang D, Yin J, Shan L, Yi X, Zhang W et al.. Identification of lysine-lactylated substrates in gastric cancer cells.. iScience 25(7):104630. 2022 Jul 15. PMID: 35800753.
[2] Yang YH, Wang QC, Kong J, Yang JT, Liu JF. Global profiling of lysine lactylation in human lungs.. Proteomics 23(15):e2200437. 2023 Aug. PMID: 37170646.
[3] Cheng Z, Huang H, Li M, Chen Y. Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells.. iScience 27(1):108645. 2024 Jan 19. PMID: 38155775.
[4] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.