Search Results
Overview
| Uniprot ID | A6NGB9 |
|---|---|
| Protein Name | WAS/WASL-interacting protein family member 3 |
| Gene Name | WIPF3 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 121 | QRDVAGGKTGQGPGS |
| 372 | RPGAGGGKLNPPPAP |
Function
May be a regulator of cytoskeletal organization. May have a role in spermatogenesis (By similarity)
Protein Sequence
10
MPVPPPPPPP
20
LPPPPPPLGA
30
PPPPPPSAPP
40
VSTDTSSLRR
50
ADPKGRSALL
60
ADIQQGTRLR
70
KVTQINDRSA
80
PQIESSKGTN
90
KEGGGSANTR
100
GASTPPTLGD
110
LFAGGFPVLR
120
PAGQRDVAGG
130
KTGQGPGSRA
140
PSPRLPNKTI
150
SGPLIPPASP
160
RLGNTSEAHG
170
AARTAPPRPN
180
VPAPPPPTPP
190
PPPPPLPPPL
200
PSSSPIKTPL
210
VSPPGPLTKG
220
NLPVVAPPVP
230
CAPPPPPPPP
240
PPTPPPLPPA
250
SVLSDKAVKP
260
QLAPLHLPPI
270
PPPLPLLPPC
280
GYPGLKAEPA
290
SPAQDAQEPP
300
APPPPLPPYA
310
SCSPRASLPA
320
PPLPGVNSSS
330
ETPPPLPPKS
340
PSFQAPPQKA
350
GAQALPAPPA
360
PPGSQPFLQK
370
KRHGRPGAGG
380
GKLNPPPAPP
390
ARSPTTELSS
400
KSQQATAWTP
410
TQQPGGQLRN
420
GSLHIIDDFE
430
SKFTFHSVED
440
FPPPDEYKPC
450
QKIYPSKIPR
460
SRTPGPWLQA
470
EAVGQSSDDI
480
KGRNSQLSLK
TLR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005769 | early endosome |
| Cellular Component | GO:0055037 | recycling endosome |
| Cellular Component | GO:0071203 | WASH complex |
| Molecular Function | GO:0003779 | actin binding |
| Molecular Function | GO:0043014 | alpha-tubulin binding |
| Biological Process | GO:0034314 | Arp2/3 complex-mediated actin nucleation |
| Biological Process | GO:0030154 | cell differentiation |
| Biological Process | GO:0032456 | endocytic recycling |
| Biological Process | GO:0006887 | exocytosis |
| Biological Process | GO:0042147 | retrograde transport, endosome to Golgi |
| Biological Process | GO:0007283 | spermatogenesis |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.
[2] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.