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Overview

Uniprot IDA6NI15
Protein NameMesogenin-1
Gene NameMSGN1
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
128 MSVQRRRKASEREKL
134 RKASEREKLRMRTLA

Function

Involved in specifying the paraxial, but not dorsal, mesoderm. May regulate the expression of T-box transcription factors required for mesoderm formation and differentiation (By similarity)

Protein Sequence

10 MDNLRETFLS 20 LEDGLGSSDS 30 PGLLSSWDWK 40 DRAGPFELNQ 50 ASPSQSLSPA 60 PSLESYSSSP 70 CPAVAGLPCE 80 HGGASSGGSE 90 GCSVGGASGL 100 VEVDYNMLAF 110 QPTHLQGGGG 120 PKAQKGTKVR 130 MSVQRRRKAS 140 EREKLRMRTL 150 ADALHTLRNY 160 LPPVYSQRGQ 170 PLTKIQTLKY 180 TIKYIGELTD 190 LLNRGREPRA QSA

Gene Ontology

Classification GO ID Description
Cellular Component GO:0000785 chromatin
Cellular Component GO:0005634 nucleus
Molecular Function GO:0003682 chromatin binding
Molecular Function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
Molecular Function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
Molecular Function GO:0046983 protein dimerization activity
Molecular Function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
Molecular Function GO:1990837 sequence-specific double-stranded DNA binding
Biological Process GO:0030154 cell differentiation
Biological Process GO:0006351 DNA-templated transcription
Biological Process GO:0001707 mesoderm formation
Biological Process GO:0006357 regulation of transcription by RNA polymerase II

Reference

PMID: N/A