Search Results
Overview
| Uniprot ID | A6NJV1 |
|---|---|
| Protein Name | Ciliary microtubule inner protein 2C |
| Gene Name | CIMIP2C |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 161 | LPPLCPKKKWHLLRL |
Function
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (PubMed:36191189). Binds to the intra-tubulin interfaces (By similarity)
Protein Sequence
10
MASRSAGTLL
20
TEFNAAYVPP
30
GLMPGYQGHV
40
PTVAFSFGAP
50
YGTTTLKYFQ
60
DHRNRAMEKS
70
HTPFSQGGHF
80
PTIFSTNPNL
90
LLMERASTRD
100
RWLHKPSYTR
110
FNLDSHRSTE
120
LTNFYQMVQQ
130
HRKYYQDKTG
140
TVPRVPYFAM
150
PVREPERYPL
160
PTVLPPLCPK
170
KKWHLLRLAP
180
ENLKTYQTFP
190
SGKRVSPQER
200
KKRDCYFEFR
A
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0160111 | axonemal A tubule inner sheath |
| Cellular Component | GO:0005879 | axonemal microtubule |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0036126 | sperm flagellum |
| Biological Process | GO:0030317 | flagellated sperm motility |
Reference
[1] Yan M, Tu H, Tang S, Gai Z, Shi Q et al.. Lactylated Proteomic Analysis Reveals Functional Implications of Lysine Lactylation In Asthenozoospermia.. Mol Cell Proteomics 24(12):101439. 2025 Dec. PMID: 41192556.