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Overview

Uniprot ID	A9UMV9
Protein Name	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
Gene Name	Ndufa7
Organism	Rattus norvegicus

Kla Sites from experimental identification

Position	Flanking peptide
101	VTPAPPMKRWELSRD
40	KRTQPPPKLPVGPSH
80	QKALVSGKTAESSAV
91	SSAVAATKRAVTPAP

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Protein Sequence

10 MASATRVIQK 20 LRNWASGQDL 30 QAKLQLRYQE 40 IAKRTQPPPK 50 LPVGPSHKLS 60 NNYYCTRDGR 70 REVVPPSIIM 80 SSQKALVSGK 90 TAESSAVAAT 100 KRAVTPAPPM 110 KRWELSRDQP YL

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005743	mitochondrial inner membrane
Cellular Component	GO:0045271	respiratory chain complex I
Biological Process	GO:0042773	ATP synthesis coupled electron transport

Reference

[1] Yao Y, Bade R, Li G, Zhang A, Zhao H et al.. Global-Scale Profiling of Differential Expressed Lysine-Lactylated Proteins in the Cerebral Endothelium of Cerebral Ischemia-Reperfusion Injury Rats.. Cell Mol Neurobiol 43(5):1989-2004. 2023 Jul. PMID: 36030297.

[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.