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Overview

Uniprot IDA9ZPH4
Protein Name-
Gene NameCCNB2
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
316 AASCLSQKVLGQGKW

Function

Essential for the control of the cell cycle at the G2/M (mitosis) transition

Protein Sequence

10 MALPRRPTVS 20 TDLENIDIGL 30 NSKPKSHVTI 40 RRAVLEEIGN 50 RVTTRATQVA 60 KKAQNIKVLV 70 PPSKTTNANK 80 PLKPTASVKP 90 VQMEMLAPKG 100 PSPTPEDMKE 110 ESLCQAFSDA 120 LLCKIEDIDN 130 EDGENPQLCS 140 DYVKDIYQYL 150 KQLEVLHPIN 160 PHFLDGRDIN 170 GRMRAILVDW 180 LVQVHSKFRL 190 LQETLYMCVA 200 IMDRFLQVQP 210 VSRKKLQLVG 220 ITALLLASKY 230 EEMFSPNIKD 240 FVYITDNAYT 250 SSQIREMETL 260 ILKELKFELG 270 RPLPLHFLRR 280 ASKAGEVDVE 290 QHTLAKYLME 300 LTLVDYDMVH 310 YHPSKVAAAA 320 SCLSQKVLGQ 330 GKWNLKQQYY 340 TGYTENEVLE 350 VMQHMAKNVM 360 KVNENLTKFI 370 AIKNKYASSK 380 LLKISTIPQL 390 NSKAIQELAS PLMGRS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005813 centrosome
Cellular Component GO:0000307 cyclin-dependent protein kinase holoenzyme complex
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005794 Golgi apparatus
Cellular Component GO:0016020 membrane
Cellular Component GO:0005815 microtubule organizing center
Cellular Component GO:0005634 nucleus
Molecular Function GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process GO:0051301 cell division
Biological Process GO:0000082 G1/S transition of mitotic cell cycle
Biological Process GO:1904145 negative regulation of meiotic cell cycle process involved in oocyte maturation

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.