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Overview

Uniprot IDB0BNC1
Protein NameLow molecular weight phosphotyrosine protein phosphatase
Gene NameAcp1
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
108 NRKSNQVKNCKAKIE
113 QVKNCKAKIELLGSY

Function

Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates with differences in substrate specificity between isoform 1 and isoform 2

Protein Sequence

10 MAEVGSKSVL 20 FVCLGNICRS 30 PIAEAVFRKL 40 VTDENVSDNW 50 AIDSSAVSDW 60 NVGRPPDPRA 70 VSCLRNHGIS 80 TAHKARQITR 90 EDFATFDYIL 100 CMDESNLRDL 110 NRKSNQVKNC 120 KAKIELLGSY 130 DPQKQLIIED 140 PYYGNDSDFE 150 VVYQQCLRCC KAFLEKTH

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Molecular Function GO:0003993 acid phosphatase activity
Molecular Function GO:0004726 non-membrane spanning protein tyrosine phosphatase activity

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.