Search Results
Overview
| Uniprot ID | B0BNE6 |
|---|---|
| Protein Name | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial |
| Gene Name | Ndufs8 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 42 | TYKYVNMKAQELDVD |
Function
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I
Protein Sequence
10
MYRLSSSVLP
20
RALAQAMRTG
30
HLNGQSLHSS
40
AVAATYKYVN
50
MKAQELDVDM
60
KSATDSAARI
70
LMWTELFRGL
80
GMTLSYLFRE
90
PATINYPFEK
100
GPLSPRFRGE
110
HALRRYPSGE
120
ERCIACKLCE
130
AICPAQAITI
140
EAEPRADGSR
150
RTTRYDIDMT
160
KCIYCGFCQE
170
ACPVDAIVEG
180
PNFEFSTETH
190
EELLYNKEKL
200
LNNGDKWEAE
210
IAANIQADYL
YR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Molecular Function | GO:0051539 | 4 iron, 4 sulfur cluster binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0008137 | NADH dehydrogenase (ubiquinone) activity |
| Molecular Function | GO:0016651 | oxidoreductase activity, acting on NAD(P)H |
| Biological Process | GO:0022904 | respiratory electron transport chain |
Reference
[1] Yao Y, Bade R, Li G, Zhang A, Zhao H et al.. Global-Scale Profiling of Differential Expressed Lysine-Lactylated Proteins in the Cerebral Endothelium of Cerebral Ischemia-Reperfusion Injury Rats.. Cell Mol Neurobiol 43(5):1989-2004. 2023 Jul. PMID: 36030297.