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Overview

Uniprot IDB0BNM9
Protein NameGlycolipid transfer protein
Gene NameGLTP
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
138 AYEMALKKYHGWLVQ

Function

Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides (By similarity)

Protein Sequence

10 MALLAEHLLK 20 PLPADRQIET 30 GPFLEAVAHL 40 PPFFDCLGSP 50 VFTPIKADIS 60 GNITKIKAVY 70 DTDPAKFKTL 80 QNILEVEKGM 90 YGAEWPKVGA 100 TLALLWLKRG 110 LRFIQVFLQS 120 ICDGERDENH 130 PNLIRVNANK 140 AYEMALKKYH 150 GWLVQKIFKA 160 ALYAAPYKSD 170 FLKALSKGQN 180 VTEEECLEKI 190 RLFLVNYTAT 200 IDAIYEMYTK MNAELDYTV

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005829 cytosol
Molecular Function GO:1902387 ceramide 1-phosphate binding
Molecular Function GO:1902388 ceramide 1-phosphate transfer activity
Molecular Function GO:0051861 glycolipid binding
Molecular Function GO:0017089 glycolipid transfer activity
Molecular Function GO:0042802 identical protein binding
Molecular Function GO:0008289 lipid binding
Molecular Function GO:0106254 lipid sensor activity
Molecular Function GO:0120013 lipid transfer activity
Biological Process GO:0035627 ceramide transport
Biological Process GO:0120009 intermembrane lipid transfer
Biological Process GO:0046317 regulation of glucosylceramide biosynthetic process
Biological Process GO:0035902 response to immobilization stress

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.