Search Results

Overview

Uniprot IDB0K031
Protein NameLarge ribosomal subunit protein uL30
Gene NameRpl7
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
10 AVPEKKKKVAAAPGT
119 GVSPKVRKVLQLLRL
168 SVNELIYKRGYGKIN
19 AAAPGTLKKKKVPAV
22 PGTLKKKKVPAVPET
235 PRGGMKKKTTHFVEG
52 LRKKFALKTLRKARR
89 RMARMARKAGNFYVP

Function

Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs

Protein Sequence

10 MEAVPEKKKK 20 VAAAPGTLKK 30 KKVPAVPETL 40 KKKRRNFAEL 50 KVKRLRKKFA 60 LKTLRKARRK 70 LIYEKAKHYH 80 KEYRQMYRTE 90 IRMARMARKA 100 GNFYVPAEPK 110 LAFVIRIRGI 120 NGVSPKVRKV 130 LQLLRLRQIF 140 NGTFVKLNKA 150 SVNMLRIVEP 160 YIAWGYPNLK 170 SVNELIYKRG 180 YGKINKKRIA 190 LTDNSLVARS 200 LGKFGIICME 210 DLIHEIYTVG 220 KRFKEANNFL 230 WPFKLSSPRG 240 GMKKKTTHFV 250 EGGDAGNRED 260 QINRLIRRMN

Gene Ontology

Classification GO ID Description
Cellular Component GO:0022625 cytosolic large ribosomal subunit
Molecular Function GO:0003723 RNA binding

Reference

[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.