Search Results
Overview
| Uniprot ID | B2CCY7 |
|---|---|
| Protein Name | Pre-mRNA-processing factor 19 |
| Gene Name | nmp-200 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 122 | RVIARLTKEVTAARE |
| 179 | IIQKLQDKATVLTTE |
| 192 | TERKKRGKTVPEELV |
| 244 | ILTGGADKNVVVFDK |
| 261 | EQILATLKGHTKKVT |
| 64 | VAHPIRPKPPSATSI |
Function
Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome
Protein Sequence
10
MSLICSISNE
20
VPEHPCVSPV
30
SNHVYERRLI
40
EKYIAENGTD
50
PINNQPLSEE
60
QLIDIKVAHP
70
IRPKPPSATS
80
IPAILKALQD
90
EWDAVMLHSF
100
TLRQQLQTTR
110
QELSHALYQH
120
DAACRVIARL
130
TKEVTAAREA
140
LATLKPQAGL
150
IVPQAVPSSQ
160
PSVVGAGEPM
170
DLGELVGMTP
180
EIIQKLQDKA
190
TVLTTERKKR
200
GKTVPEELVK
210
PEELSKYRQV
220
ASHVGLHSAS
230
IPGILALDLC
240
PSDTNKILTG
250
GADKNVVVFD
260
KSSEQILATL
270
KGHTKKVTSV
280
VFHPSQELVF
290
SASPDATIRI
300
WSVPNASCVQ
310
VVRAHESAVT
320
GLSLHATGDY
330
LLSSSDDQYW
340
AFSDIQTGRV
350
LTKVTDETSG
360
CSLTCAQFHP
370
DGLIFGTGTM
380
DSQIKIWDLK
390
ERTNVANFPG
400
HSGPITSIAF
410
SENGYYLATA
420
ADDSSVKLWD
430
LRKLKNFKTL
440
QLDNNFEVKS
450
LIFDQSGTYL
460
ALGGTDVQIY
470
ICKQWTEILH
480
FTEHSGVTTG
490
VAFGHHAKFI
500
ASTGMDRSLK
FYSL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0000974 | Prp19 complex |
| Cellular Component | GO:0071006 | U2-type catalytic step 1 spliceosome |
| Molecular Function | GO:0061630 | ubiquitin protein ligase activity |
| Molecular Function | GO:0004842 | ubiquitin-protein transferase activity |
| Biological Process | GO:0006281 | DNA repair |
| Biological Process | GO:0000398 | mRNA splicing, via spliceosome |
| Biological Process | GO:0070534 | protein K63-linked ubiquitination |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.